SEPN Stock Analysis: Septerna, Inc.

Updated Nov 3, 2026, after the Nov 2 close. Nasdaq, Biotechnology. Refreshed every trading day from the latest close.

$43.20 -1.82% Nov 2 close

The short answer

As of the Nov 2, 2026 close, QuantivFlow's Trend algo rates SEPN EXIT on the short-term (daily) horizon, a stance it has held since Sep 2, 2026 at $37.50. The mid-term (weekly) horizon reads BUY; the long-term (monthly) horizon has no confirmed signal yet, the stock's monthly history is still too short. The Rebound algo's last dip trade closed on Oct 9, 2026 at $38.37; it holds no dip position now. The Patterns algo has no active chart pattern on the daily or weekly chart. The daily RSI (14) is 61, and the price sits 10.7% above the 50-day average and 34.3% above the 200-day.

Three algos, three opinions is normal: Trend follows the established direction, Rebound buys sharp dips inside it, Patterns reads the chart shape. Not investment advice.

What Trend meansA trend-following algo. BUY while an uptrend holds on that horizon, EXIT when it breaks. Long only, judged on daily, weekly and monthly candles.
What Rebound meansA dip-buying algo. BUY after a sharp short-term drop in an otherwise healthy stock, EXIT once price closes back above its 12-day average. Short term and Mid term profiles.
What Patterns meansA chart-shape detector. Finds wedges, double tops and bottoms, cup and handle and more, marks the breakout or breakdown and measures the textbook price target. Full method

Trend

rides uptrends, long only
Short term (daily)EXIT
Mid term (weekly)BUY
Long term (monthly)No signal yet

Daily EXIT since Sep 2, 2026 at $37.50. Weekly BUY since Nov 14, 2025 at $23.26.

Rebound

buys sharp dips
Short termEXIT
Mid termEXIT

Short term: the last dip trade closed on Oct 9, 2026 at $38.37; no open dip position. Mid term: the last dip trade closed on Apr 17, 2026 at $26.13; no open dip position. The exit comes when price closes back above its 12-bar average or after 10 bars.

Patterns

chart shapes with targets
Daily and weekly chartsNo active pattern

No active chart pattern on the daily or weekly chart.

Daily indicators at the Nov 2 close

Read from the daily chart. The weekly and monthly readings are in the app.

MomentumValueRead
RSI (14)61.4strong
MACD / signal1.57 / 0.94above signal, falling
ADX (14)13.9no clear trend
+DI / -DI21.0 / 20.3buyers lead
ATR (14)2.425.6% of price
Price levelsValuevs price
SMA 2039.55+9.2%
SMA 5039.02+10.7%
SMA 20032.16+34.3%
Bollinger (20, 2)33.21 to 45.89inside the bands
52-week range17.55 to 51.1076% of range
Volume475K1.3x the 20-day average

How the algos have done on SEPN

Closed signals on this stock, from each algo's own history on the horizon named. Past results do not guarantee future results.

Trend, short term (1.1y) Not enough closed trades on this stock yet (4 so far; 5 needed).
Trend, mid term (2.0y) Not enough closed trades on this stock yet (0 so far; 5 needed).
Trend, long term Not enough closed trades on this stock yet (0 so far; 5 needed).
Rebound, short term (1.0y)
70%win rate
+3.0%avg per trade
10closed trades
Rebound, mid term (2.0y) Not enough closed trades on this stock yet (3 so far; 5 needed).
Patterns, all horizons (2y) Not enough measured breaks on this stock yet (0 detected; 5 needed).

Recent signals on SEPN

DateAlgoHorizonSignalPriceNote
2026-10-09ReboundShort term EXIT 38.37closed the BUY from Oct 6 at +7.6%
2026-10-06ReboundShort term BUY 35.67
2026-09-11ReboundShort term EXIT 38.51closed the BUY from Sep 4 at +4.8%
2026-09-04ReboundShort term BUY 36.75
2026-09-03ReboundShort term EXIT 36.80closed the BUY from Aug 20 at -9.8%
2026-09-02TrendShort term EXIT 37.50closed the BUY from $47.76 at -21.5%
2026-08-20ReboundShort term BUY 40.79
2026-08-11TrendShort term BUY 47.76later closed
2026-07-28ReboundShort term EXIT 33.97closed the BUY from Jul 16 at +7.6%
2026-07-27TrendShort term EXIT 33.49closed the BUY from $29.94 at +11.9%

The full SEPN analysis is in the QuantivFlow app

  • Chart patterns drawn on the chart, with their measured targets
  • RSI, MACD, ADX, moving averages, Bollinger Bands and volume, read for you
  • How each algo has done on SEPN: win rate, average gain, every past signal
  • A push notification the day a signal or pattern changes

Free on both stores. Scan the code with your phone, or search "QuantivFlow".

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Questions about SEPN

Is SEPN in an uptrend right now?

On weekly candles, yes; not on the others. The daily horizon is EXIT since Sep 2, 2026. The weekly horizon is BUY since Nov 14, 2025. The monthly horizon has no confirmed signal yet; the stock's monthly history is still too short. Trend is long only: BUY means the uptrend holds on that horizon, EXIT means it broke.

Is SEPN oversold?

No, the opposite: momentum is strong. The daily RSI (14) closed at 61.4; the classic oversold line is 30.

Where is SEPN's 200-day moving average?

$32.16 at the Nov 2, 2026 close, with the stock at $43.20, 34.3% above it. The 50-day average is $39.02, 10.7% below the price.

Is SEPN a buy today?

QuantivFlow does not give advice. It shows what each algo sees: Trend is EXIT on the daily horizon, Rebound holds no dip position, Patterns sees no active chart pattern. How you weigh the three depends on your horizon and risk tolerance; past signals do not guarantee future results.

Other healthcare stocks

Generated by QuantivFlow after every trading day from the same scan that powers the app. Signals describe what the algos observed on end-of-day data, not what you should do. QuantivFlow is not a broker or an investment adviser. Trading involves risk, including the loss of principal.

Data as of Nov 2, 2026 close. Page updated Nov 3, 2026 14:43 UTC. Machine-readable version: quantivflow.com/stocks/SEPN.json